Sinensis-an unfamiliar word to most but it the source of green tea,oolong
tea and black tea-different produces-also green tea has less caffeine than
black tea, etc-
polyphenols-no tannins-remember that word
as you see more and more research for polyphenols' heath benefits!-I grew up thinking
that tea's tannins were what healed-medicinalfoodnews
>LI>Curr Opin Clin Nutr Metab Care. 2003 Nov;6(6):649-56. :
Antimutagenic activity of tea: role of polyphenols.
Ioannides C, Yoxall V.
SUMMARY: PURPOSE OF REVIEW Tea is considered to be one of the most promising dietary chemopreventive agents and, consequently, it is being studied extensively worldwide. Despite the fact that tea has proved very efficient in affording protection against chemical-induced cancer in animal models of the disease, epidemiological studies do not always support the laboratory findings, so that the value of tea as a human anticarcinogen may be considered as 'not proven'. A major mechanism of the anticarcinogenic activity of tea in animals is impairment of the interaction of carcinogens with DNA leading to mutations. The antimutagenic activity of tea as well as the underlying mechanisms will be reviewed, and the role of polyphenols, the postulated bioactive components, and caffeine will be critically evaluated.RECENT FINDINGS In rats, exposure to tea modulated the disposition of heterocyclic amines, a major group of food-borne carcinogens, stimulating the pathways that lead to deactivation, and this is concordant with the established ability of tea to modulate the carcinogen-metabolizing enzyme systems. These observations provide a rational mechanism for the anticarcinogenic activity of tea in animals.SUMMARY The beneficial activities of tea have always been attributed to the polyphenols, as these are present in tea at substantial concentrations and are endowed with antioxidant activity. It is becoming increasingly evident, however, that the bioavailability of these compounds is poor as a result of limited absorption and presystemic metabolism by mammalian and microbial enzymes. We propose that the biological activity of tea may be mediated by caffeine and microbial metabolites of polyphenols.Proteomics. 2004 Jul;4(7):2160-74. :
Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells.
Wenzel U, Herzog A, Kuntz S, Daniel H.
Department of Food and Nutrition, Molecular Nutrition Unit, Technical University of Munich, Hochfeldweg 2, D-85350 Freising-Weihenstephan, Germany.
A high dietary intake of plant foods is thought to contribute to the prevention of colorectal cancers in humans and flavonoids as part of such a diet are considered to contribute to those protective effects. Quercetin is a major dietary flavonoid consumed with a diet rich in onions, tea, and apples. We used HT-29 human colon cancer cells and investigated the effects of quercetin on proliferation, apoptosis, and differentiation as processes shown to be disregulated during cancer development. To identify the cellular targets of quercetin action, two-dimensional gel electrophoresis was performed and proteins altered in expression level after quercetin exposure of cells were identified by mass spectrometry of peptide fragments generated by tryptic digestion. Quercetin inhibited the proliferation of HT-29 cells with an IC(50)-value of 81.2 +/- 6.6 microM. Cell differentiation based on surface expression of alkaline phosphatase was enhanced 4-fold and the activity of the pro-apoptotic effector caspase-3 increased 3-fold. Those effects were associated with the regulation of heat-shock proteins and annexins shown to both play a crucial role in the process of apoptosis. Cytoskeletal caspase substrates were found as regulated as well and various proteins involved in intermediary metabolism and in gene regulation showed altered steady-state expression levels upon quercetin treatment of cells. In conclusion, quercetin alters the levels of a variety of proteins involved in growth, differentiation, and apoptosis of colon cancer cells. Their identification as molecular targets of quercetin may explain the anti-cancer activities of this flavonoid.
J Nutr. 2003 Oct;133(10):3262S-3267S. :
Mechanisms of cancer prevention by tea constituents.
Lambert JD, Yang CS.
Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Consumption of tea (Camellia sinensis) has been suggested to prevent cancer, heart disease and other diseases. Animal studies have shown that tea and tea constituents inhibit carcinogenesis of the skin, lung, oral cavity, esophagus, stomach, liver, prostate and other organs. In some studies, the inhibition correlated with an increase in tumor cell apoptosis and a decrease in cell proliferation. Studies with human cancer cell lines have demonstrated that epigallocatechin-3-gallate (EGCG), a major tea polyphenol, inhibits mitogen-activated protein kinases, cyclin-dependent kinases, growth factor-related cell signaling, activation of activator protein 1 (AP-1) and nuclear factor kappaB (NFkappaB), topoisomerase I and matrix metalloproteinases as well as other potential targets. Although some studies report effects of EGCG at submicromolar levels, most experiments require concentrations of >10 or 20 micromol/L to demonstrate the effect. In humans, tea polyphenols undergo glucuronidation, sulfation, methylation, and ring fission. The peak plasma concentration of EGCG is approximately 1 micromol/L. The possible relevance of each of the proposed mechanisms to human cancer prevention is discussed in light of current bioavailability data for tea polyphenols and the potential limitations of animal models of carcinogenesis. Such discussion, it is hoped, will clarify some misunderstandings of cancer prevention by tea and stimulate new research efforts.Tea polyphenols inhibit the formation of mutagens during the cooking of
"Powerful mutagens are formed during the broiling or frying of meat. These mutagens cause
specific cancers in animal models, and epidemiological studies suggest that they increase the risk of
breast and colon cancer. It is important, therefore, to inhibit the formation of these mutagens.
Application of tea polyphenols, polyphenon 60((R)) from green tea, and polyphenon B((R)) from
black tea, to both surfaces of ground beef before cooking inhibits the formation of the mutagens in a
dose-related fashion. This procedure is simple and effective, and utilizes inexpensive tea, a product
that deserves consideration for practical use" tea and coffee drinking may reduce risk of
developing Parkinson's Diseaseclick here..notice not herbal tea but tea with caffeine Catechin intake might explain the inverse relation between tea
consumption and ischemic heart disease: the Zutphen Elderly Study.
"Epidemiologic studies suggest that tea consumption may reduce the risk of
cardiovascular diseases, but results are inconsistent. Catechins, which belong to the flavonoid
family, are the main components of tea and may be responsible for the alleged protective effect.""There
was no association between catechin intake and stroke incidence or mortality. CONCLUSION:
Catechins, whether from tea or other sources, may reduce the risk of ischemic heart disease
mortality but not of stroke.""Epidemiologic studies suggest an inverse association of tea consumption with cardiovascular
disease...Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for
"Collectively, the antioxidant effects of flavonoid-rich foods
may reduce cardiovascular disease risk."Regular ingestion of black tea improves brachial artery vasodilator
"A higher intake of black tea has been associated with lower cardiovascular disease risk. The
antioxidant effects of tea polyphenols may enhance endothelial function and thereby reduce the
risk of coronary events.
suggest that one mechanism by which black tea may reduce cardiovascular risk is via improved
vasodilator function of conduit arteries."tea drinking can possibly decrease risk of strokes and heart disease"Tea
also provides more than 15 per cent of our daily requirement of calcium
and 10 per cent of folic acid as well as 45 per cent of our manganese requirement.
"-also sounds like a cheap and safe source for calcium, etcResearch showing beneficial effects of drinking tea and heart disease"Endothelial dysfunction has been associated with coronary artery disease and increased
oxidative stress. Antioxidants have been shown to reverse endothelial dysfunction and tea
contains antioxidant flavonoids. "
Although we are aware that tea can stain your teeth if you don't watch out, tea
is a natural source of fluoride-helpful to teeth and gums;tea may also help prevent
plaque build up by increasing saliva which acts against acid
TEA FOR ORAL HEALH-notice they play down teeth stainingTeaTea is an antioxidant-antioxidant computer eyes or whatever-put warm teabags on eyes for compresses-lie down for 15 minutes-it really works!soak your smelly or tired feet in a tea solution-helps rid foot odor and soothes tired feetput used tea bag on stings-bee or poison ivy etc-gets rid
of sting or itchdebate as to whether it is soothing and healing for burns-it works for
meplace warm teabag a few times a day on plantar's wart-although garlic cloves might work fasterhave friends who have used tea bags as natural tint for their hairhave
friends who have used tea to unify color in stained light fabrics-antique the antique
guess good for no longer white socks-give them that natural lookif you find the right
tea color, might be good way of repairing a stained spot of woodmight try putting used
tea leaves in refrigator to help remove odor-but baking soda etc would probably work better
clean varnished wood with cold tea(becareful of shade of tea)
also supposedly good for laquered wood
read up on benefits of GREEN TEA-supposedly has an ingredient that counteracts caffeine-
research appears to be showing great anti cancer propertiesa lot of people recycle their used tea leaves and create fertilizer for their houseplants-gardenias etcsome
use tea as part of a facial-astringent like properties-again soothing
The tannin in tea is a natural meat tenderizer.
Pakistan is closing in on United Kingdom's number one ranking as leading country importer
India is the world's largest tea producer, consumer and exporter of black tea.
square tea bags were introduced in 1951 to British consumers
Tea for immunity
"Tea drinkers produce interferon – coffee drinkers do not
Then, two weeks into the study, the researchers tested the blood of coffee and tea drinkers by exposing it to bacteria in the lab and comparing samples taken before the study to those taken two weeks later. "We found they [tea drinkers] made five times more interferon after they started drinking tea compared to before drinking tea," Bukowski says. The coffee drinkers showed no enhanced production of interferon.
Not all teas contain L-theanine, Bukowski cautions. Green, black, oolong, or pekoe teas do.
"Tea may offer protection against infections and ailments
If the research bears out, tea drinking may prove to offer protection from skin infections caused by bacteria, bacterial pneumonias, and food poisoning, among other ailments, according to Bukowski"